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Lorem ipsum dolor sit nulla or narjusto laoreet onse ctetur adipisci. Using a combination product makes it challenging to know how much of the beneficial effect came from comfrey alone. Retrieved from https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295, Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., & Staiger, C. (2005). Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. The Herbal Academy supports trusted organizations with the use of affiliate links. Stop using comfrey and call your healthcare provider at once if you have: liver problems--nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes). View abstract. J Chiropr Med. Please read the Topical Use Safety section of this article (above) before using. There are no regulated manufacturing standards in place for many herbal compounds and some marketed supplements have been found to be contaminated with toxic metals or other drugs. Two interesting studies found that a topical application of a product containing comfrey root extract helped with knee pain and stiffness. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. Centurian, South Africa: Medpharm Scientific Publishers. Company number 02758955 Registered VAT number 211727395. Comfrey [Online article]. Additionally, because its alkaloids are absorbed through the skin, use of comfrey as a poultice should not exceed an exposure of 100 mcg/day of the alkaloids. Comfrey is an herb in the Boraginaceae family and has small purple flowers. how to become a school board member in florida ocean deck band schedule , 43 volunteers with osteoarthritis used either a topical cream containing comfrey, tannic acid, and eucalyptus or a placebo cream 3x/ day for 6 weeks. Mackinnon, M. In general practice, 'always expect the unexpected'. (2004). Looks like you may need to upgrade your browser We're sorry, we no longer support the web browser that you are using Using a supplement like comfrey may have potential side effects. radix) extract ointment in the treatment of patients with painful osteoarthritis of the knee: results of a double-blind, randomised, bicenter, placebo-controlled trial. View abstract. However, not a rate considered harmful for those with healthy livers.10,11, Masters Degree in Toxicology and BSc Hons in Medical Biochemistry. Avoid with medications that induce CYP3A4 or are hepatotoxic (Natural Medicines, 2020). View abstract. Eucalyptus oil is used externally to stimulate blood flow. This is not a complete list of side effects and others may occur. Comfrey is considered likely unsafe to use if you are nursing a baby. Topical preparations of comfrey are generally safe provided they are not applied excessively or to an open wound. Vithayathil MK, Edwards M. Comfrey herbal remedy causing second-degree heart block: do not be outfoxed by digitalis. We comply with the HONcode standard for trustworthy health information. View abstract. We comply with the HONcode standard for trustworthy health information. Comfrey oil should be applied topically to parts of the body where you have muscular pain or discomfort. Not all possible interactions are listed in this product guide. However, further well-designed studies are needed. Food and Drug Administration. What Are the Side Effects of Comfrey Cream? Satisfaction. Symphyti) in the treatment of ankle distorsions: Results of a multicenter, randomized, placebo-controlled, double-blind study. In 2001, the Food and Drug Administration (FDA) banned oral comfrey products. You and your healthcare provider should weigh the pros and cons and use it only under their supervision. Squish and squeeze as many leaves into as you can into the container. (2018). Pabst H, Schaefer A, Staiger C, Junker-samek M, Predel HG. Palestrica of the Third Millennium Civilization & Sport. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. Verywell Health's content is for informational and educational purposes only. Do not take comfrey without medical advice if you are using any of the following medications: This list is not complete. Chojkier M. Hepatic sinusoidal-obstruction syndrome: toxicity of pyrrolizidine alkaloids. It contains chemicals that are poisonous. It should never be taken by mouth. Comfrey has been claimed to heal gastric ulcers and hemorrhoids, and to suppress bronchial congestion and inflammation. Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Call your doctor if the condition you are treating with comfrey does not improve, or if it gets worse while using this product. While there can be a variety of causes for back pain, these small studies offer hopeful results that comfrey root may offer potential analgesic and anti-inflammatory benefits. Rad. Additionally, there is scientific research demonstrating comfreys effectiveness at soothing muscle and joint pain, some of which are highlighted in this post. Oral use of comfrey is not recommended because of potential liver damage. This site uses cookies to improve your experience. Do not use this product if you have a sensitivity to any of the ingredients. To make the cream, combine sunflower oil, safflower oil, coconut oil, and cocoa butter in a double-boiler over low heat until completely melted. DOI:10.1211/PJ.2021.1.69803. View abstract. Comfrey cream, an topical herbal product, is thought to reduce inflammation and pain when applied to the skin. To make this recipe, first, you must prepare the comfrey root tincture. Avoid using comfrey together with other herbal/health supplements that can also harm the liver. 7-6-2001; Lin, C. C., Yang, C. C., Phua, D. H., Deng, J. F., and Lu, L. H. An outbreak of foxglove leaf poisoning. Can a comfrey (Symphytum officianale) root extraction help ease aching joints and muscles? Tanret, I. and Duh, D. [Pharmaceutical sheet. Scientific studies have shown comfrey oil can help reduce the likelihood leg ulcers will become infected.7, Topical application of comfrey oil has been shown to support the lower and upper back more than methyl nicotinate, the main ingredient in many muscle creams.8. The review included one study of 220 people with knee osteoarthritis, a degenerative "wear-and-tear" joint condition. 2023 Dotdash Media, Inc. All rights reserved, Verywell Health uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. 4.3 4.3 out of 5 stars (225) $19.95 $ 19. 1/8 cup comfrey tincture (Symphytum officinale), store bought or via recipe, above. Set aside cup for the cream recipe and store the rest in a glass jar. Kucera, M., Barna, M., Horacek, O., Kalal, J., Kucera, A., and Hladikova, M. Topical symphytum herb concentrate cream against myalgia: a randomized controlled double-blind clinical study. Make sure to always buy comfrey. The chemicals contained in comfrey may cause birth defects. Do not use this product without medical advice if you are breast-feeding a baby. Check regularly, but it should take about six weeks for all the leaves to break down into a thick, black liquid. Join Rewards for Life today and we'll give you 300 points worth 3, Save 5% on your favourite products, plus get the lowest price from the last 90 days and free delivery on orders over 10. Many of those following the folk use of comfrey up to present-day think so. Turley, A. J. and Muir, D. F. ECG for physicians: a potentially fatal case of mistaken identity. The roots and leaves of the comfrey plant have medicinal properties. Comfrey oil is a herbal oil that moisturises skin, and that's been used as a healing herb for a long time. In a multicenter, randomized, double-blind, placebo-controlled study with 142 ankle sprain participants, a comfrey root extract applied 4x/day for 8 days improved pain, swelling, and mobility without any adverse reactions (Koll et al., 2004). Phytomedicine, 14(1), 2-10. https://doi.org/10.1016/j.phymed.2006.11.006, Jedlinszki, N., Balzs, B., Csnyi, E., & Csupor, D. (2017). 2018;19(5):455-474. doi:10.1016/j.jpain.2017.11.005, Gagnier JJ, Oltean H, van Tulder MW, Berman BM, Bombardier C, Robbins CB. In a double-blind, randomized, placebo-controlled study involving 120 patients with acute back pain, symptoms were quickly reduced in the group using 4 grams of an ointment containing 35% comfrey root extract 3x/day for 5 days (Giannetti et al., 2010). Using different formulations together increases the risk of an overdose. 2021;83:e249209. J Agric.Food Chem 2001;49(8):3942-3946. Comfrey cream contains several active components (substances). Comfrey has also been used for the following conditions: There is currently not enough evidence to recommend comfrey cream for any of these uses. A limited number of clinical trials show short-term efficacy of topically applied, alkaloid-free comfrey preparations in skin abrasions and inflammatory conditions. Topical comfrey is for use only on the skin. Adv Ther 2005;22(6):681-692. Symphytum officinale L., dermal use (Flexagile cream)]. View abstract. 1 Since at least the 4 th century, people have used comfrey medicinally. . The first European settlers of America considered comfrey so indispensable, they carried it on their journey across the Atlantic in the 1600s.2. View abstract. Comfrey is not recommended for internal use because of the liver damage caused by its pyrrolizidine alkaloids. A handbook for practice on a scientific basis. The efficacy and safety of a homeopathic gel in the treatment of acute low back pain: a multi-centre, randomised, double-blind comparative clinical trial. Also, avoid use for more than two weeks or excessive concentrations containing more than 100 mcg of pyrrolizidine alkaloids (Wichtl, 2004 & Ulbricht, 2010). Cochrane Database Syst Rev. To make this recipe, first, you must prepare the comfrey root tincture. Since these toxic substances can be absorbed through the skin, there's concern about the safety of comfrey cream applied topically. Grube, B., Grnwald, J., Krug, L., & Staiger, C. (2007). The combination of Vitamin E, Wheat Germ oil and Rice Bran oil makes this cream perfect for your daily hydration needs. Some drugs increase how quickly the liver changes and breaks down comfrey. View abstract. Choose organically grown comfrey when possible. Centurian, South Africa: Medpharm Scientific Publishers. J Chiropr Med. Browse our Sports Hub, Get 20% student discount with Student Beans, Discover the latest natural beauty products, Buy 1 get 1 Half Price on Vitamins & Supplements, Popular Vitamins & Supplements Subscriptions, Buy 1 get 1 Half Price gut health supplements, Guide to sleeping better natural sleeping remedies, Living in the now, gut health & mental wellbeing, The thing that makes you different makes you special, For the symptomatic relief of minor sprains and bruises, Contains Comfrey which is known for its healing properties. All rights reserved. Nat Prod Res 2018;32(5):605-9. doi: 10.1080/14786419.2017.1326492. The use of babosa (Aloe vera) in treating burns: a literature review. Medicinal use of this product has not been approved by the FDA. Smith, D. B., & Jacobson, B. H. (2011). For this reason, some topical products are advertised as made from comfrey leaves, but it's safest to choose a PA-free product. The groups using the herbal preparations reported a significantly greater reduction in pain and stiffness associated with osteoarthritis of the knee without serious adverse reactions (Smith & Jacobson, 2011). My family has used comfy for ingrown toenails. Wien.Med Wochenschr. This is the tincture. comfrey: [noun] any of a genus (Symphytum) of perennial herbs of the borage family with coarse hairy entire leaves and flowers in one-sided racemes. Pour into bowl /jug big enough for all ingredients and safe for the mixer. View abstract. Wound-healing effects of a symphytum herb extract cream (. (2001). J Hepatol 2003;39:437-46. Predel, H. G., Giannetti, B., Koll, R., Bulitta, M., and Staiger, C. Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study. Koll, R., Buhr, M., Dieter, R., Pabst, H., Predel, H. G., Petrowicz, O., & Staiger, C. (2004). Of course, more research is needed to validate efficacy and safety. One study in 120 patients with acute upper or lower back pain used either four grams (g) of comfrey root ointment or a placebo (sham treatment) three times daily for five days. Mei N, Guo L, Fu PP, Fuscoe JC, Luan Y, Chen T. Metabolism, genotoxicity, and carcinogenicity of comfrey. Readers must do their own research concerning the safety and usage of any herbs or supplements. Efficacy of a comfrey root extract ointment in comparison to a Diclo-fenac gel in the treatment of ankle distortions: Results of an observer-blind, randomized, multicenter study. Cap, then label the jars with the date made and ingredients. In another study, participants with ankle sprains received either comfrey root extract cream or diclofenac gel, a nonsteroidal anti-inflammatory drug (NSAID). Can comfrey be used for cracked nipples during breastfeeding? Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. 2019;24(12):2272. doi:10.3390/molecules24122272, Staiger, Christine. Wound-healing effects of a symphytum herb extract cream (Symphytum uplandicum Nyman) in children: A randomized double-blind study. Osteoarthritis Cartilage. Comfrey cream byBhupesh Panchal, Senior Regulatory Affairs Associate, Comfrey oil is a herbal oil that moisturises skin, and thats been used as a healing herb for a long time.1, Since at least the 4th century, people have used comfrey medicinally. It may contain small amounts of toxic pyrrolizidine alkaloids. Comfrey has long been used in folk traditions for bruising and abrasions. Retrieved from, https://naturalmedicines.therapeuticresearch.com/databases/food,-herbs-supplements/professional.aspx?productid=295. Discard after a year or according to labeling. 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